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Issue 17, 2004

Biotinylated CdSe/ZnSe nanocrystals for specific fluorescent labeling

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Abstract

A set of two new surface ligands is presented for the preparation of water-soluble, biotinylated CdSe/ZnSe core/shell nanocrystals, suitable for fluorescent biological labeling. It consists of a thiolated diethyleneglycol derivative and an alkylthiol substituted biotin molecule, which replace the initial capping ligands at the nanocrystal surface. Successful ligand exchange and long-term photostability of the modified nanocrystals as well as their highly specific binding to neuronal cells are demonstrated in different labeling experiments.

Graphical abstract: Biotinylated CdSe/ZnSe nanocrystals for specific fluorescent labeling

Article information


Submitted
10 Mar 2004
Accepted
27 May 2004
First published
18 Jun 2004

J. Mater. Chem., 2004,14, 2638-2642
Article type
Paper

Biotinylated CdSe/ZnSe nanocrystals for specific fluorescent labeling

N. Charvet, P. Reiss, A. Roget, A. Dupuis, D. Grünwald, S. Carayon, F. Chandezon and T. Livache, J. Mater. Chem., 2004, 14, 2638 DOI: 10.1039/B403714F

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