The Barbier Reaction of 1-(Chloromethyl)benzotriazole with Aldehydes and Ketones mediated by Samarium Diiodide
Abstract
1-(Chloromethyl)benzotriazole can smoothly undergo the SmI2–Barbier reaction with aldehydes and ketones to give 1-β-(hydroxyalkyl)benzotriazoles under very mild conditions.