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Issue 8, 2008
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Multiple molecular simultaneous imaging in a live mouse using semiconductor Compton camera

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Abstract

We have demonstrated the feasibility of semiconductor Compton cameras for multiple molecular imaging in nuclear medicine. The Compton camera used in this work comprises two double-sided orthogonal-strip germanium detectors, and their excellent energy resolution enabled discrimination of the nuclides and accurate determination of the scattering angle for γ rays in wide energy range. Three radioactive tracers of 65ZnCl2, 85SrCl2, and iodinated (131I) methylnorcholestenol were injected to a living mouse and were measured simultaneously. Both two- and three-dimensional images of each tracer were obtained by a fixed-angle imaging with a single Compton camera, which reflected the different in vivo behavior of them.

Graphical abstract: Multiple molecular simultaneous imaging in a live mouse using semiconductor Compton camera

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Article information


Submitted
20 Feb 2008
Accepted
11 Jun 2008
First published
08 Jul 2008

J. Anal. At. Spectrom., 2008,23, 1089-1092
Article type
Paper

Multiple molecular simultaneous imaging in a live mouse using semiconductor Compton camera

S. Motomura, Y. Kanayama, H. Haba, Y. Watanabe and S. Enomoto, J. Anal. At. Spectrom., 2008, 23, 1089
DOI: 10.1039/B802964D

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