Allenes. Part XVIII. The synthesis of allenic amino-acids from allenic bromides and diethyl formylaminomalonate
Abstract
The preparation of six allenic amino-acids from 1-bromoalka-1,2-, -2,3-, and -3,4-dienes and diethyl formylamino-malonate is described. Iodoallene gave only the formylamino(prop-2-ynyl)malonate, which on hydrolysis gave prop-2-ynylglycine. 5-Bromopent-3-en-1-yne gave 2-aminohept-4-en-6-ynoic acid in excellent yield.