Jump to main content
Jump to site search

Issue 0, 1970
Previous Article Next Article

Crystal structure of the hydrobromide of 1-p-(2-dimethylaminoethoxyphenyl)-1,2-cis-diphenylbut-1-ene, a compound with oestrogenic activity

Abstract

The crystal structure of the hydrobromide of 1-p-(2-dimethylaminoethoxyphenyl)-1,2-cis-diphenylbut-1-ene, a compound with oestrogenic activity, has been determined from diffractometer data and refined to R 0·101 for 3082 planes. The compound crystallizes in the triclinic system with Z= 4; the structure has refined satisfactorily in the space group P[1 with combining macron]. There are two crystallographically distinct conformational isomers of the cation in the crystal, differing mainly in the torsion angle in the O–CH2–CH2–N+ chain [+60° and –176°, syn-clinal-(gauche) and anti-periplanar(trans) conformations respectively]. The average dihedral angle between the planes of the aromatic rings and the plane of the ethylenic double bond is 54°. The identification of the isomers of similar related tri-aryl ethylenes from their n.m.r. spectra can now be made with confidence by reference to this known structure.

Back to tab navigation

Article information


J. Chem. Soc. B, 1970, 1-5
Article type
Paper

Crystal structure of the hydrobromide of 1-p-(2-dimethylaminoethoxyphenyl)-1,2-cis-diphenylbut-1-ene, a compound with oestrogenic activity

B. T. Kilbourn and P. G. Owston, J. Chem. Soc. B, 1970, 1
DOI: 10.1039/J29700000001

Search articles by author

Spotlight

Advertisements