Stability of N-heterocyclic oxime derivatives. Part III. The kinetics of the hydrolysis of formyl- and acetyl-pyridine O-acetyloximes in aqueous solution in the pH range 6·0–10·8 at 25, 35, and 40°

Abstract

The hydrolysis of the formyl- and acetyl-pyridine O-acetyloximes, O-acetylbenzaldoxime, and acetophenone O-acetyloxime in aqueous solution in the pH range 6–10·8 have been studied. The end-products of the reactions have been analysed, and it has been shown that quantitative yields of the parent oximes are obtained. The Hammett equation has been found to be valid both for the reaction of the O-acetyl derivatives of the pyridine aldoximes and the 1-methylpyridinium aldoxime iodides with hydroxyl ions yielding the parent oximes, and to the similar reaction of the corresponding O-acetylketoximes. The reaction constants, ρ_ald and ρ_ket are 0·607 and 0·526 respectively.