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Issue 2, 2011
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Chemically-coupled-peptide-promoted virus nanoparticle templated mineralization

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The external surface of the plant virus Cowpea mosaic virus (CPMV) can be chemically modified with peptides that direct specific mineralization processes. Subsequent mineralization of the peptide-CPMV conjugates produces monodisperse nanoparticles of ca. 32 nm diameter coated with, for example, cobaltplatinum, ironplatinum or zinc sulfide, which cannot be readily prepared by other methods. This route is particularly attractive as it avoids the need to genetically engineer the protein surface of the virus to provide chimaeras for templated-mineralization. The synthetic procedure is environmentally friendly, as it proceeds at ambient temperature and pressure, in aqueous solvent. Further, the methodology is demonstrated to be generally applicable by the mineralization of a peptide-modified multiwalled carbon nanotube.

Graphical abstract: Chemically-coupled-peptide-promoted virus nanoparticle templated mineralization

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Publication details

The article was received on 21 Jun 2010, accepted on 30 Sep 2010 and first published on 28 Oct 2010

Article type: Paper
DOI: 10.1039/C0IB00056F
Citation: Integr. Biol., 2011,3, 119-125

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