Jump to main content
Jump to site search

Issue 8, 2019
Previous Article Next Article

Solvent and catalyst free synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones by twin screw extrusion

Author affiliations

Abstract

This report describes the synthesis of a few 3,4-dihydropyrimidin-2(1H)-ones/thiones using a twin screw extruder. Use of the extruder allowed the reaction to be carried out without a catalyst or solvent. Twin screw extrusion can also be executed as a continuous process and is easy to scale up.

Graphical abstract: Solvent and catalyst free synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones by twin screw extrusion

Back to tab navigation

Supplementary files

Publication details

The article was received on 05 Jan 2019, accepted on 18 Mar 2019 and first published on 25 Mar 2019


Article type: Communication
DOI: 10.1039/C9GC00036D
Green Chem., 2019,21, 1921-1924

  •   Request permissions

    Solvent and catalyst free synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones by twin screw extrusion

    R. B. Carvalho and S. V. Joshi, Green Chem., 2019, 21, 1921
    DOI: 10.1039/C9GC00036D

Search articles by author

Spotlight

Advertisements