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Issue 13, 2016
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Development of GSK's NMR guides – a tool to encourage the use of more sustainable solvents

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Abstract

Residual solvents often appear as nuisance signals in experimental NMR spectra, and many chemists turn to well-known literature sources to quickly identify such peaks. While these publications are very useful, they do not currently include many solvents exemplified in green chemistry-related literature. This work provides a single compiled reference for NMR chemical shifts of 80 solvents in each of 6 deuterated NMR solvents. The overall green chemistry assessments, as reached via the methodology of the GSK Solvent Sustainability Guide, are displayed on these charts.

Graphical abstract: Development of GSK's NMR guides – a tool to encourage the use of more sustainable solvents

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Article information


Submitted
16 Feb 2016
Accepted
15 Apr 2016
First published
15 Apr 2016

Green Chem., 2016,18, 3867-3878
Article type
Paper

Development of GSK's NMR guides – a tool to encourage the use of more sustainable solvents

H. E. Gottlieb, G. Graczyk-Millbrandt, G. G. A. Inglis, A. Nudelman, D. Perez, Y. Qian, L. E. Shuster, H. F. Sneddon and R. J. Upton, Green Chem., 2016, 18, 3867
DOI: 10.1039/C6GC00446F

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