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Issue 11, 2013
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Practical metal-free synthesis of chalcone derivatives via a tandem cross-dehydrogenative-coupling/elimination reaction

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Abstract

Metal-free synthesis of chalcone derivatives through a tandem cross-dehydrogenative-coupling/elimination reaction is described. A simple and inexpensive ammonium persulfate salt enables the reaction between ketones and benzylamines to proceed with high stereoselectivity and good functional group compatibility.

Graphical abstract: Practical metal-free synthesis of chalcone derivatives via a tandem cross-dehydrogenative-coupling/elimination reaction

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Article information


Submitted
16 Jul 2013
Accepted
25 Aug 2013
First published
27 Aug 2013

Green Chem., 2013,15, 3165-3169
Article type
Communication

Practical metal-free synthesis of chalcone derivatives via a tandem cross-dehydrogenative-coupling/elimination reaction

Y. Wei, J. Tang, X. Cong and X. Zeng, Green Chem., 2013, 15, 3165
DOI: 10.1039/C3GC41403E

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