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Issue 6, 2010
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Solvent-free microwave-assisted Meyers’ lactamization

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Abstract

Microwave solvent-free conditions developed for Meyers’ lactamization, a typical bielectrophile-binucleophile reaction that produces quaternary centers in a stereoselective manner, give access to Meyers’ chiral lactams in good yield and high diastereoselectivity in short times.

Graphical abstract: Solvent-free microwave-assisted Meyers’ lactamization

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Submitted
19 Nov 2009
Accepted
06 Apr 2010
First published
30 Apr 2010

Green Chem., 2010,12, 961-964
Article type
Communication

Solvent-free microwave-assisted Meyers’ lactamization

M. Jida, R. Deprez-Poulain, S. Malaquin, P. Roussel, F. Agbossou-Niedercorn, B. Deprez and G. Laconde, Green Chem., 2010, 12, 961
DOI: 10.1039/B924111F

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