Issue 3, 2010

A simple, efficient and green procedure for Knoevenagel condensation catalyzed by [C4dabco][BF4] ionic liquid in water

Abstract

A convenient and rapid method for Knoevenagel condensation has been developed by using DABCO-base ionic liquid catalysts. This method is applicable to a wide range of aromatic/aliphatic/heterocyclic/α,β-unsaturated aldehydes and ketones with active methylene compounds, and affords the corresponding substituted electrophilic alkenes in excellent yields (up to 100%) in water at room temperature within short times. The method is operationally simple and the products do not need to be purified. The use of water as the reaction medium makes the process environmentally benign. The catalysts can be recycled seven times without activity loss.

Graphical abstract: A simple, efficient and green procedure for Knoevenagel condensation catalyzed by [C4dabco][BF4] ionic liquid in water

Supplementary files

Article information

Article type
Paper
Submitted
09 Sep 2009
Accepted
21 Nov 2009
First published
29 Jan 2010

Green Chem., 2010,12, 514-517

A simple, efficient and green procedure for Knoevenagel condensation catalyzed by [C4dabco][BF4] ionic liquid in water

D. Xu, Y. Liu, S. Shi and Y. Wang, Green Chem., 2010, 12, 514 DOI: 10.1039/B918595J

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