Issue 5, 2009

Combined action of enzymes: the first domino reaction catalyzed by Agaricus bisporus

Abstract

The enzymes tyrosinase and laccase from a crude extract of the button mushroom (Agaricus bisporus) can be employed to catalyze the domino reaction between phenol and various cyclic 1,3-dicarbonyls using atmospheric oxygen as the oxidizing agent and yielding annulated benzofuranes in a highly efficient and sustainable manner.

Graphical abstract: Combined action of enzymes: the first domino reaction catalyzed by Agaricus bisporus

Article information

Article type
Communication
Submitted
24 Dec 2008
Accepted
18 Feb 2009
First published
27 Feb 2009

Green Chem., 2009,11, 676-679

Combined action of enzymes: the first domino reaction catalyzed by Agaricus bisporus

H. Leutbecher, S. Hajdok, C. Braunberger, M. Neumann, S. Mika, J. Conrad and U. Beifuss, Green Chem., 2009, 11, 676 DOI: 10.1039/B822977E

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