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Issue 9, 2004
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Strategic biocatalysis with hyperthermophilic enzymes

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With the advent of genome sequence information, in addition to capabilities for cloning and expressing genes of interest in foreign hosts, a wide range of hyperthermophilic enzymes have become accessible for potential applications for biocatalytic processes. Not only can these enzymes be useful for strategic opportunities at high temperatures, but there may also be advantages that derive from their relatively low activity at suboptimal temperatures. Examples of several possible ways in which hyperthermophilic enzymes could be used are presented, including cases where they could serve as environmentally benign alternatives in existing industrial processes.

Graphical abstract: Strategic biocatalysis with hyperthermophilic enzymes

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The article was received on 27 Apr 2004, accepted on 08 Jun 2004 and first published on 19 Aug 2004

Article type: Critical Review
DOI: 10.1039/B406297C
Green Chem., 2004,6, 459-465

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    Strategic biocatalysis with hyperthermophilic enzymes

    D. A. Comfort, S. R. Chhabra, S. B. Conners, C. Chou, K. L. Epting, M. R. Johnson, K. L. Jones, A. C. Sehgal and R. M. Kelly, Green Chem., 2004, 6, 459
    DOI: 10.1039/B406297C

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