Issue 4, 2004

Aqueous N-alkylation of amines using alkyl halides: direct generation of tertiary amines under microwave irradiation

Abstract

Direct formation of tertiary amines viaN-alkylation of amines by alkyl halides occurs in aqueous media under microwave irradiation. This greener alternative is also a useful and powerful method to construct C–N bond without using any transition metal catalysts.

Graphical abstract: Aqueous N-alkylation of amines using alkyl halides: direct generation of tertiary amines under microwave irradiation

Article information

Article type
Paper
Submitted
03 Feb 2004
Accepted
20 Feb 2004
First published
17 Mar 2004

Green Chem., 2004,6, 219-221

Aqueous N-alkylation of amines using alkyl halides: direct generation of tertiary amines under microwave irradiation

Y. Ju and R. S. Varma, Green Chem., 2004, 6, 219 DOI: 10.1039/B401620C

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