Impact of pH changes on metal oxide nanoparticle behaviour during artificial digestion

Abstract

The physicochemical properties of orally ingested metal nanoparticles can be influenced by the conditions prevailing in the digestive tract. In our work, we demonstrate the strong influence of the pH value on particle fate using a simplified digestion approach to analyze magnesium oxide, copper oxide and zinc oxide nanoparticles and show why a separate consideration of the digestion parameters is necessary.