Jump to main content
Jump to site search

Issue 9, 2018

Application of a commercial digestive supplement formulated with enzymes and probiotics in lactase non-persistence management

Author affiliations

Abstract

Strategies to avoid lactose malabsorption, which affects 70% of the world's population, are focused on the restriction of milk and dairy products or the use of non-human β-galactosidases or probiotics endowed with β-galactosidase activity added at mealtime. Our evaluation of a commercial blend of probiotics and enzymes (protease, lactase, lipase and amylase) and its potential application in lactase non-persistence management is described in this work. Recommended amounts (460–1000 mg) of the commercial probiotics–enzyme blend were shown to be adequate for performing in vitro lactose hydrolysis in standard solutions (0.25–5%) and commercial dairy products, namely milks (5% lactose) and yogurts (3% lactose), reaching hydrolysis values between 44 and 96%. According to these percentages, the use of the enzymatic preparation would guarantee the intake of less than 12 g, the recommendation of the EFSA for lactose intolerance. Furthermore, formation of prebiotic galactooligosaccharides was also detected, increasing the potential benefits of the enzymatic preparation in the gastrointestinal system.

Graphical abstract: Application of a commercial digestive supplement formulated with enzymes and probiotics in lactase non-persistence management

Article information


Submitted
31 May 2018
Accepted
30 Jul 2018
First published
02 Aug 2018

Food Funct., 2018,9, 4642-4650
Article type
Paper

Application of a commercial digestive supplement formulated with enzymes and probiotics in lactase non-persistence management

A. Ferreira-Lazarte, F. J. Moreno and M. Villamiel, Food Funct., 2018, 9, 4642 DOI: 10.1039/C8FO01091A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.


Social activity

Search articles by author

Spotlight

Advertisements