Jump to main content
Jump to site search

Issue 1, 2012
Previous Article Next Article

Protective effects of Allium paradoxum against gentamicin-induced nephrotoxicity in mice

Author affiliations

Abstract

Allium paradoxum (M.Bieb.) G. Don is a locally known vegetable and is utilized for preparation a variety of local foods in northern of Iran. This study was conducted to quantitatively evaluate the recovery effects of A. paradoxum on gentamicin-induced nephrotoxicity in mice. The curative effect of extracts from the aerial parts and bulbs of A. paradoxum against gentamicin-induced renotoxicity in mice was determined. Both extracts at the dose 200 mg kg−1 day−1 offered nephroprotective effect by change in the blood urea nitrogen and creatinine. No statistical difference could be obtained in serum creatinine and blood urea nitrogen of bulb-treated mice compared to normal mice. The result show that bulb extract at 200 mg kg−1 day−1 has better activity than aerial parts.

Graphical abstract: Protective effects of Allium paradoxum against gentamicin-induced nephrotoxicity in mice

Back to tab navigation

Article information


Submitted
22 Aug 2011
Accepted
15 Oct 2011
First published
28 Oct 2011

Food Funct., 2012,3, 28-29
Article type
Communication

Protective effects of Allium paradoxum against gentamicin-induced nephrotoxicity in mice

S. F. Nabavi, S. M. Nabavi, A. H. Moghaddam, A. Naqinezhad, R. Bigdellou and S. Mohammadzadeh, Food Funct., 2012, 3, 28
DOI: 10.1039/C1FO10173K

Social activity

Search articles by author

Spotlight

Advertisements