Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Volume 169, 2014
Previous Article Next Article

Exploring genomes with a game engine

Author affiliations

Abstract

More and more evidence indicates that the 3D conformation of eukaryotic genomes is a critical part of genome function. However, due to the lack of accurate and reliable 3D genome structural data, this information is largely ignored and most of these studies have to use information systems that view the DNA in a linear structure. Visualizing genomes in real time 3D can give researchers more insight, but this is fraught with hardware limitations since each element contains vast amounts of information that cannot be processed on the fly. Using a game engine and sophisticated video game visualization techniques enables us to construct a multi-platform real-time 3D genome viewer. The game engine-based viewer achieves much better rendering speed and can handle much larger amounts of data compared to our previous implementation using OpenGL. Combining this viewer with 3D genome models from experimental data could provide unprecedented opportunities to gain insight into the conformation–function relationships of a genome.

Back to tab navigation

Article information


Submitted
20 Dec 2013
Accepted
20 Mar 2014
First published
20 Mar 2014

Faraday Discuss., 2014,169, 443-453
Article type
Paper
Author version available

Exploring genomes with a game engine

J. J. Shepherd, L. Zhou, W. Arndt, Y. Zhang, W. J. Zheng and J. Tang, Faraday Discuss., 2014, 169, 443
DOI: 10.1039/C3FD00152K

Social activity

Search articles by author

Spotlight

Advertisements