Issue 14, 2020

A tri-metallic palladium complex with breast cancer stem cell potency

Abstract

A multi-nuclear, triangular-shaped palladium(II) complex is shown to equipotently kill bulk cancer cells and cancer stem cells (CSCs) in the micromolar range. The palladium(II) complex evokes CSC apoptosis by entering CSC nuclei and damaging genomic DNA.

Graphical abstract: A tri-metallic palladium complex with breast cancer stem cell potency

Supplementary files

Article information

Article type
Communication
Submitted
01 Jan 2020
Accepted
07 Mar 2020
First published
09 Mar 2020

Dalton Trans., 2020,49, 4211-4215

A tri-metallic palladium complex with breast cancer stem cell potency

A. Eskandari, A. Kundu, A. Johnson, S. Karmakar, S. Ghosh and K. Suntharalingam, Dalton Trans., 2020, 49, 4211 DOI: 10.1039/D0DT00006J

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