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Issue 43, 2012
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The prevalence of metal-based drugs as therapeutic or diagnostic agents: beyond platinum

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Abstract

Metal complexes and metal salts have a wide range of medicinal applications and are extensively administered to patients or purchased over the counter as a matter of routine. The abundance and variety of non-platinum metal complexes, which are approved for use as therapeutic or diagnostic agents, are highlighted. Current insights into the mechanism of action or indeed lack thereof of a selection of metallodrugs are discussed. Ultimately this perspective seeks to inspire chemists to tackle new challenges and raise awareness of opportunities in the area of inorganic therapeutic and diagnostic medicine.

Graphical abstract: The prevalence of metal-based drugs as therapeutic or diagnostic agents: beyond platinum

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Article information


Submitted
18 Jul 2012
Accepted
17 Aug 2012
First published
20 Aug 2012

Dalton Trans., 2012,41, 13239-13257
Article type
Perspective

The prevalence of metal-based drugs as therapeutic or diagnostic agents: beyond platinum

D. Gaynor and D. M. Griffith, Dalton Trans., 2012, 41, 13239
DOI: 10.1039/C2DT31601C

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