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Issue 4, 2012
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Ruthenium complexes containing bis-benzimidazole derivatives as a new class of apoptosis inducers

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Abstract

A series of ruthenium complexes containing bis-benzimidazole derivatives have been synthesized and identified as able to target mitochondria and induce caspase-dependent apoptosis in cancer cells through superoxide overproduction.

Graphical abstract: Ruthenium complexes containing bis-benzimidazole derivatives as a new class of apoptosis inducers

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Publication details

The article was received on 16 Oct 2011, accepted on 15 Nov 2011 and first published on 09 Dec 2011


Article type: Communication
DOI: 10.1039/C1DT11950H
Dalton Trans., 2012,41, 1138-1141

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    Ruthenium complexes containing bis-benzimidazole derivatives as a new class of apoptosis inducers

    L. Li, Y. Wong, T. Chen, C. Fan and W. Zheng, Dalton Trans., 2012, 41, 1138
    DOI: 10.1039/C1DT11950H

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