Indole-Based Chemosensor for Hg2+ and Cu2+ Ions: Applications in Molecular Switches and Live Cell Imaging

Paramjit Kaur; Sandeep Kaur; Kamaljit Singh; Parduman Raj Sharma; Tandeep Kaur

doi:10.1039/C1DT11076D

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Indole-Based Chemosensor for Hg²⁺ and Cu²⁺ Ions: Applications in Molecular Switches and Live Cell Imaging†

Paramjit Kaur,*^a Sandeep Kaur,^ab Kamaljit Singh,*^b Parduman Raj Sharma^c and Tandeep Kaur^c

Author affiliations

* Corresponding authors

^a Department of Chemistry, UGC-Center for Advance Studies-1, Guru Nanak Dev University, Amritsar, India
E-mail: paramjit19in@yahoo.co.in

^b Organic Synthesis Laboratory, Department of Applied Chemical Sciences and Technology, Guru Nanak Dev University, Amritsar, India

^c Department of Cancer Pharmacology, Indian Institute of Integrative Medicine (IIIM), Canal Road, Jammu, India
E-mail: kamaljit19in@yahoo.co.in

Abstract

An indole based “ratiometric” and “turn-off” tris(N-methylindolyl)methane based chemosensor depicting a contrasting fluorescent behavior towards Hg²⁺ and Cu²⁺ ions, exhibited NOR and YES logic functions, and also imaged intracellular Hg²⁺ in cervix cancer (HeLa) cells.

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Article information

DOI: https://doi.org/10.1039/C1DT11076D
Article type: Communication
Submitted: 08 Jun 2011
Accepted: 04 Aug 2011
First published: 20 Sep 2011

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Dalton Trans., 2011,40, 10818-10821

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Indole-Based Chemosensor for Hg²⁺ and Cu²⁺ Ions: Applications in Molecular Switches and Live Cell Imaging

P. Kaur, S. Kaur, K. Singh, P. R. Sharma and T. Kaur, Dalton Trans., 2011, 40, 10818 DOI: 10.1039/C1DT11076D

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Dalton Transactions