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Issue 23, 2011
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Metallic radionuclides in the development of diagnostic and therapeutic radiopharmaceuticals

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Abstract

Metallic radionuclides are the mainstay of both diagnostic and therapeutic radiopharmaceuticals. Therapeutic nuclear medicine is less advanced but has tremendous potential if the radionuclide is accurately targeted. Great interest exists in the field of inorganic chemistry for developing target specific radiopharmaceuticals based on radiometals for non-invasive disease detection and cancer radiotherapy. This perspective will focus on the nuclear properties of a few important radiometals and their recent applications to developing radiopharmaceuticals for imaging and therapy. Other topics for discussion will include imaging techniques, radiotherapy, analytical techniques, and radiation safety. The ultimate goal of this perspective is to introduce inorganic chemists to the field of nuclear medicine and radiopharmaceutical development, where many applications of fundamental inorganic chemistry can be found.

Graphical abstract: Metallic radionuclides in the development of diagnostic and therapeutic radiopharmaceuticals

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Article information


Submitted
04 Mar 2011
Accepted
30 Mar 2011
First published
03 May 2011

Dalton Trans., 2011,40, 6112-6128
Article type
Perspective

Metallic radionuclides in the development of diagnostic and therapeutic radiopharmaceuticals

S. Bhattacharyya and M. Dixit, Dalton Trans., 2011, 40, 6112
DOI: 10.1039/C1DT10379B

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