Jump to main content
Jump to site search

Issue 1, 2011
Previous Article Next Article

Chiral N-heterocyclic biscarbenes based on 1,2,4-triazole as ligands for metal-catalyzed asymmetric synthesis

Author affiliations

Abstract

A facile and straightforward synthetic procedure for the preparation of new chiral bis-1,2,4-triazolium salts and their corresponding rhodium(I) biscarbene complexes are reported. It is widely applicable for the synthesis of 1,2,4-triazolium salts. The new chiral biscarbenes represent promising ligands for transition metal-catalyzed asymmetric syntheses. Their first successful application is demonstrated by the rhodium-catalyzed hydrogenation of dimethylitaconate and methyl-2-acetamidoacrylate which yielded enantioselectivities of up to 61% ee.

Graphical abstract: Chiral N-heterocyclic biscarbenes based on 1,2,4-triazole as ligands for metal-catalyzed asymmetric synthesis

Back to tab navigation

Supplementary files

Article information


Submitted
24 Jun 2010
Accepted
18 Oct 2010
First published
09 Nov 2010

Dalton Trans., 2011,40, 41-43
Article type
Communication

Chiral N-heterocyclic biscarbenes based on 1,2,4-triazole as ligands for metal-catalyzed asymmetric synthesis

S. K. U. Riederer, B. Bechlars, W. A. Herrmann and F. E. Kühn, Dalton Trans., 2011, 40, 41
DOI: 10.1039/C0DT00724B

Social activity

Search articles by author

Spotlight

Advertisements