Molecular “light switch” for G-quadruplexes and i-motif of human telomeric DNA: [Ru(phen)2(dppz)]2+

Shuo Shi; Juan Zhao; Xiaoting Geng; Tianming Yao; Hailiang Huang; Tianlin Liu; Lengfeng Zheng; Zonghui Li; Danjing Yang; Liangnian Ji

doi:10.1039/B916094A

Molecular “light switch” for G-quadruplexes and i-motif of human telomeric DNA: [Ru(phen)₂(dppz)]²⁺†

Shuo Shi,*^a Juan Zhao,^a Xiaoting Geng,^a Tianming Yao,*^a Hailiang Huang,^a Tianlin Liu,^a Lengfeng Zheng,^a Zonghui Li,^a Danjing Yang^a and Liangnian Ji^ab

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^a Department of Chemistry, Tongji University, Shanghai, China
E-mail: shishuo@tongji.edu.cn, tmyao@tongji.edu.cn
Fax: +86-21-6598-2287
Tel: +86-21-6598-3292

^b MOE Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou, China

Abstract

[Ru(phen)₂(dppz)]²⁺can serve as a prominent molecular “light switch” for G-quadruplexes and i-motif, but it preferentially binds to G-quadruplexes over i-motif.

Dalton Transactions

Molecular “light switch” for G-quadruplexes and i-motif of human telomeric DNA: [Ru(phen)₂(dppz)]²⁺†

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Molecular “light switch” for G-quadruplexes and i-motif of human telomeric DNA: [Ru(phen)₂(dppz)]²⁺

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