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Issue 13, 2016
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Fine chemical syntheses under flow using SiliaCat catalysts

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After reviewing selected recent applications from diverse laboratories, we show how mesoporous organosilica-entrapped catalysts of the SiliaCat series have been successfully used for clean manufacturing of APIs in a number of different reactions carried out under laminar flow in microreactors. The advantages and disadvantages linked to these catalysts in terms of technical and economical sustainability are highlighted. Insight into the scale-up of this technique and related catalytic technologies from the lab scale to industrial production concludes the study.

Graphical abstract: Fine chemical syntheses under flow using SiliaCat catalysts

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Publication details

The article was received on 07 Jan 2016, accepted on 04 Mar 2016 and first published on 10 Mar 2016

Article type: Perspective
DOI: 10.1039/C6CY00038J
Catal. Sci. Technol., 2016,6, 4678-4685

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    Fine chemical syntheses under flow using SiliaCat catalysts

    R. Ciriminna, V. Pandarus, F. Béland and M. Pagliaro, Catal. Sci. Technol., 2016, 6, 4678
    DOI: 10.1039/C6CY00038J

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