Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 15, 2019
Previous Article Next Article

Strategies for designing organic fluorescent probes for biological imaging of reactive carbonyl species

Author affiliations

Abstract

Reactive carbonyl species (RCS) are involved not only in diverse physiological pathways but also in various pathological processes, including Alzheimer's disease, diabetes, cardiovascular disease, and other malignant diseases. Therefore, it is essential to develop a simple and sensitive technology which can be employed to selectively monitor RCS in living biological samples, such as living cells, tissues, and animals. The subtle changes in the concentration of RCS in organisms can be detected by this technique. In this review, the design strategies of the typical examples of RCS fluorescent probes are highlighted and discussed. These advanced RCS probes may set the foundation for biomedical research on dynamic real-time monitoring of RCS in living systems.

Graphical abstract: Strategies for designing organic fluorescent probes for biological imaging of reactive carbonyl species

Back to tab navigation

Supplementary files

Article information


Submitted
05 Mar 2019
First published
12 Jun 2019

Chem. Soc. Rev., 2019,48, 4036-4048
Article type
Tutorial Review

Strategies for designing organic fluorescent probes for biological imaging of reactive carbonyl species

Y. Tang, Y. Ma, J. Yin and W. Lin, Chem. Soc. Rev., 2019, 48, 4036
DOI: 10.1039/C8CS00956B

Social activity

Search articles by author

Spotlight

Advertisements