Quinone-based fluorophores for imaging biological processes
Quinones are privileged chemical structures playing crucial roles as redox and alkylating agents in a wide range of processes in cells. The broad functional array of quinones has prompted the development of new chemical approaches, including C–H bond activation and asymmetric reactions, to generate probes for examining their activity by means of fluorescence imaging. This tutorial review covers recent advances in the design, synthesis and applications of quinone-based fluorescent agents for visualizing specific processes in multiple biological systems, from cells to tissues and complex organisms in vivo.
- This article is part of the themed collections: Probes for in vitro and in vivo fluorescence imaging, 2018 Emerging Investigators and SBQ-RSC: Celebrating UK-Brazil collaborations