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Issue 8, 2016
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Synthesis of α-aminoboronic acids

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Abstract

This review describes available methods for the preparation of α-aminoboronic acids in their racemic or in their enantiopure form. Both, highly stereoselective syntheses and asymmetric procedures leading to the stereocontrolled generation of α-aminoboronic acid derivatives are included. The preparation of acyclic, carbocyclic and azacyclic α-aminoboronic acid derivatives is covered. Within each section, the different synthetic approaches have been classified according to the key bond which is formed to complete the α-aminoboronic acid skeleton.

Graphical abstract: Synthesis of α-aminoboronic acids

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Article information


Submitted
01 Dec 2015
First published
08 Feb 2016

This article is Open Access

Chem. Soc. Rev., 2016,45, 2291-2307
Article type
Review Article

Synthesis of α-aminoboronic acids

P. Andrés, G. Ballano, M. I. Calaza and C. Cativiela, Chem. Soc. Rev., 2016, 45, 2291
DOI: 10.1039/C5CS00886G

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