Issue 6, 2006

The therapeutic application of lanthanides

Abstract

The biological properties of the lanthanides, based on their similarity to calcium, have stimulated research into their therapeutic application. Historical medical uses of the lanthanides and recent advances and successes will be described in the context of the biological chemistry of lanthanides, including a new metal-based drug, lanthanum carbonate, which has recently been approved as a phosphate binder for the treatment of hyperphosphatemia. This tutorial review will be of interest to those working on metal-based drugs, including inorganic chemists, and biological scientists.

Graphical abstract: The therapeutic application of lanthanides

Article information

Article type
Tutorial Review
Submitted
11 Apr 2006
First published
28 Apr 2006

Chem. Soc. Rev., 2006,35, 524-533

The therapeutic application of lanthanides

S. P. Fricker, Chem. Soc. Rev., 2006, 35, 524 DOI: 10.1039/B509608C

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