Jump to main content
Jump to site search

Issue 4, 2000
Previous Article Next Article

A surface chemistry approach to studying cell adhesion

Author affiliations

Abstract

Model substrates that present peptide and carbohydrate ligands are becoming important mechanistic tools in cell biology. This review surveys the development of self-assembled monolayers of alkanethiolates on gold as a model substrate for studies of cell adhesion. The review begins with a background that illustrates the opportunity for using tailored substrates in biology and then addresses the characteristics that make monolayers well-suited for these studies. The review concludes with a discussion of recent work that is developing dynamic substrates wherein the activity of immobilized ligands can be modulated in real time.

Back to tab navigation

Article information


Submitted
10 Feb 2000
First published
05 Jun 2000

Chem. Soc. Rev., 2000,29, 267-273
Article type
Review Article

A surface chemistry approach to studying cell adhesion

M. Mrksich, Chem. Soc. Rev., 2000, 29, 267
DOI: 10.1039/A705397E

Social activity

Search articles by author

Spotlight

Advertisements