Issue 12, 2019

Dynamics of proteins confined in non-ionic bicontinuous microemulsions: a FCS study

Abstract

In our present work we present an approach which allows one to confine proteins in structurally nearly identical bicontinuous microemulsions with systematically decreasing water domain size. It is shown that sub-diffusive behaviour occurs already at water domain sizes below 13 nm. However, above 13 nm normal diffusion is seen. Moreover, we compare protein diffusion in microemulsions to the transport of a much smaller fluorescent dye.

Graphical abstract: Dynamics of proteins confined in non-ionic bicontinuous microemulsions: a FCS study

Supplementary files

Article information

Article type
Paper
Submitted
15 Oct 2018
Accepted
02 Mar 2019
First published
04 Mar 2019

Phys. Chem. Chem. Phys., 2019,21, 6725-6731

Dynamics of proteins confined in non-ionic bicontinuous microemulsions: a FCS study

O. Wrede, S. Großkopf, T. Seidel and T. Hellweg, Phys. Chem. Chem. Phys., 2019, 21, 6725 DOI: 10.1039/C8CP06419A

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