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Issue 26, 2015
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Loop nucleotides impact the stability of intrastrand i-motif structures at neutral pH

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Abstract

The stability of i-motif structures at neutral pH is of interest due to the potential of these structures to impact gene expression. A systematic investigation of loop sequence and length revealed that certain loop nucleobases stabilize i-motif quadruplexes.

Graphical abstract: Loop nucleotides impact the stability of intrastrand i-motif structures at neutral pH

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Article information


Submitted
14 May 2015
Accepted
26 May 2015
First published
26 May 2015

Phys. Chem. Chem. Phys., 2015,17, 16719-16722
Article type
Communication
Author version available

Loop nucleotides impact the stability of intrastrand i-motif structures at neutral pH

T. Fujii and N. Sugimoto, Phys. Chem. Chem. Phys., 2015, 17, 16719
DOI: 10.1039/C5CP02794B

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