Protein synthesis in artificial cells: using compartmentalisation for spatial organisation in vesicle bioreactors†
Abstract
Whereas spatial organisation of function is ubiquitous in biology, it has been lacking in artificial cells. We rectify this by using multi-compartment vesicles as chassis for artificial cells, allowing distinct biological processes to be isolated in space. This is demonstrated by in vitro synthesis of two proteins in predefined vesicle regions.
- This article is part of the themed collection: Chemical compartmentalisation by membranes: from biological mechanism to biomimetic applications