Jump to main content
Jump to site search

Issue 40, 2012
Previous Article Next Article

Protonreduction to hydrogen in biological and chemical systems

Author affiliations


In the drive to devise catalytic systems to convert solar energy into the energy of chemical bonds, chemists and electrochemists are seeking inspiration from our understanding of enzymes involved in bioenergetics. This is particularly true for generating molecular hydrogen from high energy electrons derived from solar driven water splitting. In this case the natural enzymes are the [NiFe]- and [FeFe]-hydrogenases. In this article we review our present understanding of the structure and mechanistic functioning of these enzymes and how they are providing a blue print to the design and understanding of the mechanism of a variety of synthesized catalysts for proton reduction chemistry.

Graphical abstract: Proton reduction to hydrogen in biological and chemical systems

Back to tab navigation

Publication details

The article was received on 16 Jul 2012, accepted on 16 Aug 2012 and first published on 10 Sep 2012

Article type: Perspective
DOI: 10.1039/C2CP42413D
Phys. Chem. Chem. Phys., 2012,14, 13772-13784

  •   Request permissions

    Proton reduction to hydrogen in biological and chemical systems

    P. D. Tran and J. Barber, Phys. Chem. Chem. Phys., 2012, 14, 13772
    DOI: 10.1039/C2CP42413D

Search articles by author