Issue 29, 2012
From the journal:

Physical Chemistry Chemical Physics

Enhanced stabilization of the Tobacco mosaic virus using protic ionic liquids†

Nolene Byrne,*a   Brendan Rodoni,b   Fiona Constable,b   Swapna Varghesea  and  James H. Davis, Jr.*c  

* Corresponding authors

a Centre for Material and Fibre Innovation, Institute of Frontier Materials, Deakin University, Geelong

b Victorian Department of Primary Industries, Knoxfield Centre, Private Bag 15, Ferntree Gully Delivery Centre, Victoria, Australia

c Department of Chemistry, University of South Alabama, Mobile, USA
E-mail: nolene.byrne@deakin.edu.au

Abstract

We report on the use of protic ionic liquids, pILs, as solvents for the solubilisation and stabilization of viruses. We show that the shelf life of the pIL stabilized tobacco mosaic virus is significantly enhanced when compared to traditional phosphate buffer. This has new opportunities for the preparation, characterization and storage of viruses and virus based technologies.

Graphical abstract: Enhanced stabilization of the Tobacco mosaic virus using protic ionic liquids

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Article information

DOI
https://doi.org/10.1039/C2CP41625E
Article type
Communication
Submitted
19 May 2012
Accepted
11 Jun 2012
First published
27 Jun 2012

Phys. Chem. Chem. Phys., 2012,14, 10119-10121

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Enhanced stabilization of the Tobacco mosaic virus using protic ionic liquids

N. Byrne, B. Rodoni, F. Constable, S. Varghese and J. H. Davis, Phys. Chem. Chem. Phys., 2012, 14, 10119 DOI: 10.1039/C2CP41625E

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