Issue 14, 2010
From the journal:

Physical Chemistry Chemical Physics

Dynamics of heparan sulfate explored by neutron scattering†

Marion Jasnin,‡a   Lambert van Eijck,a   Michael Marek Koza,a   Judith Peters,abc   Cédric Laguri,b   Hugues Lortat-Jacobb  and  Giuseppe Zaccai*ab  

* Corresponding authors

a Institut Laue-Langevin, 6 rue Jules Horowitz, 38042 Grenoble Cedex 9, France
E-mail: zaccai@ill.fr
Fax: +33 47620 7120
Tel: +33 47620 7679

b Institut de Biologie Structurale, 41 rue Jules Horowitz, 38027 Grenoble Cedex 1, France

c Université Joseph Fourier, UFR de Physique, 38041 Grenoble Cedex 9, France

Abstract

The temperature dependence of atomic fluctuations in heparan sulfate was measured for different time-scales between the picosecond and the nanosecond. The data established the role of hydration for the emergence of high-amplitude motions at 200–240 K, and the higher resilience of the polysaccharide compared to proteins measured under similar conditions.

Graphical abstract: Dynamics of heparan sulfate explored by neutron scattering

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Article information

DOI
https://doi.org/10.1039/B923878F
Article type
Communication
Submitted
13 Nov 2009
Accepted
16 Feb 2010
First published
01 Mar 2010

Phys. Chem. Chem. Phys., 2010,12, 3360-3362

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Dynamics of heparan sulfate explored by neutron scattering

M. Jasnin, L. van Eijck, M. Marek Koza, J. Peters, C. Laguri, H. Lortat-Jacob and G. Zaccai, Phys. Chem. Chem. Phys., 2010, 12, 3360 DOI: 10.1039/B923878F

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