Structural changes of poly-l-lysine in solution and lyophilized form
Abstract
Two structural changes of poly-L-lysine have been studied by various spectroscopic techniques; one is a structural change of a random coil sample in solution to a mixture of α-helix and β-sheet during rapid freezing in the lyophilizing process, and the other is a pressure-induced structural change from an α-helix to a β-sheet structure for a lyophilized sample.