Twisting of the resorcinarene core due to solvent effects upon crystallization

Abstract

The effect of the crystallization conditions on the conformation of the tetramethoxy resorcinarene skeleton was investigated in acetone solutions, to which was added a second component (less favorable solvent or salt) to promote crystallization. The resorcinarene core was found to adopt three different conformations: crown (I), a pinched crown (II) and a twisted pinched crown (III). In addition, the flexibility of the resorcinarene core was compared with a tetramethoxy resorcinarene derivative, resorcinarene bis-crown, which is in a fixed boat conformation.