Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 21st October 2020 from 07:00 AM to 07:00 PM (BST).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 73, 2020
Previous Article Next Article

A versatile strategy to synthesize N-methyl-anthranilic acid-labelled glycoprobes for fluorescence-based screening assays

Author affiliations

Abstract

Here we propose a general strategy to label carbohydrates with N-methyl-anthranilic acid at the anomeric position. Through two examples, we demonstrate that the generated glycoprobes are suitable for fluorescence-based binding/competition assays. Our approach is expected to readily generate series of glycoprobes dedicated to screening assays for the discovery of drugs targeting carbohydrate–protein interactions.

Graphical abstract: A versatile strategy to synthesize N-methyl-anthranilic acid-labelled glycoprobes for fluorescence-based screening assays

Back to tab navigation

Supplementary files

Article information


Submitted
03 Jun 2020
Accepted
03 Aug 2020
First published
12 Aug 2020

Chem. Commun., 2020,56, 10746-10749
Article type
Communication

A versatile strategy to synthesize N-methyl-anthranilic acid-labelled glycoprobes for fluorescence-based screening assays

I. Bertin-Jung, A. Robert, N. Ramalanjaona, S. Gulberti, C. Bui, J. Vincourt, M. Ouzzine, J. Jacquinet, C. Lopin-Bon and S. Fournel-Gigleux, Chem. Commun., 2020, 56, 10746
DOI: 10.1039/D0CC03882B

Social activity

Search articles by author

Spotlight

Advertisements