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Issue 43, 2020
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Purine-blended nanofiber woven flexible nanomats for SERS-based analyte detection

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Abstract

Flexible and free-standing polymeric fibers, coupled with metal nanoparticles, present an excellent opportunity for highly sensitive surface-enhanced Raman scattering (SERS) spectroscopy-based detection platforms. Such host matrices are prepared by only a few preferred methods, followed by induction of metal nanoparticle aggregation in a protected environment to afford functional SERS platforms. We provide an interesting advance in this area by choosing a thiol-modified purine (L)–polymer blend, obtained through the electrospinning process, for directed decoration with gold nanoparticles. The described SERS purine-nanomat substrate enables the detection of uric acid, an important indicator of gout, preeclampsia, cardiovascular and kidney diseases, in aqueous solution up to 100 nM, with good stability and high sensitivity, offering superiority over existing techniques in terms of sensitivity and cost-effectiveness.

Graphical abstract: Purine-blended nanofiber woven flexible nanomats for SERS-based analyte detection

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Supplementary files

Article information


Submitted
23 Jan 2020
Accepted
16 Apr 2020
First published
16 Apr 2020

Chem. Commun., 2020,56, 5795-5798
Article type
Communication

Purine-blended nanofiber woven flexible nanomats for SERS-based analyte detection

R. K. Saravanan, T. K. Naqvi, S. Patil, P. K. Dwivedi and S. Verma, Chem. Commun., 2020, 56, 5795
DOI: 10.1039/D0CC00648C

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