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Issue 56, 2020
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Novel copper-based and pH-sensitive nanomedicine for enhanced chemodynamic therapy

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Abstract

We utilized albumin as a reducing agent to establish novel copper-based and pH-sensitive nanocarrier CuNPs with abundant Cu+, which can encapsulate histone deacetylase (HDAC) inhibitor vorinostat to form uniform and stable nanomedicine V-CuNPs for synergistic chromatin remodelling and chemodynamic therapy.

Graphical abstract: Novel copper-based and pH-sensitive nanomedicine for enhanced chemodynamic therapy

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Supplementary files

Article information


Submitted
08 Jan 2020
Accepted
03 Jun 2020
First published
02 Jul 2020

Chem. Commun., 2020,56, 7753-7756
Article type
Communication

Novel copper-based and pH-sensitive nanomedicine for enhanced chemodynamic therapy

L. Wang, Z. Zhang, Y. Ding, J. Wu, Y. Hu and A. Yuan, Chem. Commun., 2020, 56, 7753
DOI: 10.1039/D0CC00165A

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