Issue 12, 2020

Conformationally rigid pyrazoloquinazoline α-amino acids: one- and two-photon induced fluorescence

Abstract

The synthesis and photophysical properties of a new class of α-amino acid bearing a rigid pyrazoloquinazoline chromophore are described. Confromational constraint of the amino acid side-chains resulted in high emission quantum yields, while the demonstration of two-photon-induced fluorescence via near-IR excitation signifies their potential for sensitive bioimaging applications.

Graphical abstract: Conformationally rigid pyrazoloquinazoline α-amino acids: one- and two-photon induced fluorescence

Supplementary files

Article information

Article type
Communication
Submitted
21 Nov 2019
Accepted
13 Jan 2020
First published
13 Jan 2020
This article is Open Access
Creative Commons BY license

Chem. Commun., 2020,56, 1887-1890

Conformationally rigid pyrazoloquinazoline α-amino acids: one- and two-photon induced fluorescence

J. D. Bell, A. H. Harkiss, D. Nobis, E. Malcolm, A. Knuhtsen, C. R. Wellaway, A. G. Jamieson, S. W. Magennis and A. Sutherland, Chem. Commun., 2020, 56, 1887 DOI: 10.1039/C9CC09064A

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