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Issue 3, 2020
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Accelerated DNAzyme-based fluorescent nanoprobe for highly sensitive microRNA detection in live cells

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Abstract

By assembling DNAzyme on DNA nanowires through DNA hybridization, we have developed a novel accelerated DNAzyme-based fluorescent nanoprobe for fast, sensitive and selective detection of miRNA. Moreover, the strategy was successfully applied for in situ imaging of miRNA-21 in different cell lines.

Graphical abstract: Accelerated DNAzyme-based fluorescent nanoprobe for highly sensitive microRNA detection in live cells

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Article information


Submitted
04 Nov 2019
Accepted
04 Dec 2019
First published
04 Dec 2019

Chem. Commun., 2020,56, 470-473
Article type
Communication

Accelerated DNAzyme-based fluorescent nanoprobe for highly sensitive microRNA detection in live cells

Y. Wu, H. Meng, J. Chen, K. Jiang, R. Yang, Y. Li, K. Zhang, L. Qu, X. Zhang and Z. Li, Chem. Commun., 2020, 56, 470
DOI: 10.1039/C9CC08598J

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