Issue 1, 2020

Internal standard fluorogenic probe based on vibration-induced emission for visualizing PTP1B in living cells

Abstract

Herein, as a proof of concept, we developed the first enzymatic VIE fluorogenic probe for protein tyrosine phosphatase 1B (PTP1B). The detection and imaging of PTP1B using VIE in living cells were both realized. Particularly importantly, the designed probe herein provides a guideline and platform for the development of new VIE-based enzymatic probes.

Graphical abstract: Internal standard fluorogenic probe based on vibration-induced emission for visualizing PTP1B in living cells

Supplementary files

Article information

Article type
Communication
Submitted
30 Sep 2019
Accepted
23 Oct 2019
First published
25 Oct 2019

Chem. Commun., 2020,56, 58-61

Internal standard fluorogenic probe based on vibration-induced emission for visualizing PTP1B in living cells

Q. Gong, W. Qin, P. Xiao, X. Wu, L. Li, G. Zhang, R. Zhang, J. Sun, S. Q. Yao and W. Huang, Chem. Commun., 2020, 56, 58 DOI: 10.1039/C9CC07680H

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