Issue 100, 2019

Aggregation-induced emission-active Au nanoclusters for ratiometric sensing and bioimaging of highly reactive oxygen species

Abstract

We prepared a nanoprobe through self-assembly of gold nanoclusters (AuNCs) and using FITC-modified hyaluronic acid (HA) for ratiometric sensing of highly reactive oxygen species (hROS). Taking advantage of the aggregation-induced emission (AIE) properties of the self-assembled AuNCs, hROS-responsive cleavage of HA, and the ratiometric signal change of dual-emission, the nanoprobe exhibited excellent performance in imaging hROS in living cells.

Graphical abstract: Aggregation-induced emission-active Au nanoclusters for ratiometric sensing and bioimaging of highly reactive oxygen species

Supplementary files

Article information

Article type
Communication
Submitted
18 Oct 2019
Accepted
22 Nov 2019
First published
23 Nov 2019

Chem. Commun., 2019,55, 15097-15100

Aggregation-induced emission-active Au nanoclusters for ratiometric sensing and bioimaging of highly reactive oxygen species

X. Ran, Z. Wang, F. Pu, Z. Liu, J. Ren and X. Qu, Chem. Commun., 2019, 55, 15097 DOI: 10.1039/C9CC08170D

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