Issue 88, 2019

A NIR-emitting cyanine with large Stokes shifts for live cell imaging: large impact of the phenol group on emission

Abstract

There are a limited number of near-infrared (NIR) emitting (λem = 700–900 nm) molecular probes for imaging applications. A NIR-emitting probe that exhibits emission at ∼800 nm with a large Stokes shift was synthesized and found to exhibit excellent selectivity towards mitochondria for live-cell imaging. The photophysical properties were attributed to an excited “cyanine structure” via intramolecular charge transfer (ICT) involving a phenol group.

Graphical abstract: A NIR-emitting cyanine with large Stokes shifts for live cell imaging: large impact of the phenol group on emission

Supplementary files

Article information

Article type
Communication
Submitted
02 Sep 2019
Accepted
26 Sep 2019
First published
26 Sep 2019

Chem. Commun., 2019,55, 13223-13226

A NIR-emitting cyanine with large Stokes shifts for live cell imaging: large impact of the phenol group on emission

D. Dahal, L. McDonald, S. Pokhrel, S. Paruchuri, M. Konopka and Y. Pang, Chem. Commun., 2019, 55, 13223 DOI: 10.1039/C9CC06831G

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