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Issue 86, 2019
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Etchable SERS nanosensor for accurate pH and hydrogen peroxide sensing in living cells

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Abstract

No methodology has been built to distinguish intracellular SERS nanosensors from cell outer membrane bound-ones. Here we propose a “turning off” strategy by combining etchable SERS nanosensors with a non-permeable etchant. The SERS signals outside the living cells can be rapidly removed, leaving only the internalized nanosensors for imaging and thereby allowing accurate intracellular pH and H2O2 sensing.

Graphical abstract: Etchable SERS nanosensor for accurate pH and hydrogen peroxide sensing in living cells

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Article information


Submitted
21 Aug 2019
Accepted
03 Oct 2019
First published
04 Oct 2019

Chem. Commun., 2019,55, 12996-12999
Article type
Communication

Etchable SERS nanosensor for accurate pH and hydrogen peroxide sensing in living cells

L. Bai, X. Wang, K. Zhang, X. Tan, Y. Zhang and W. Xie, Chem. Commun., 2019, 55, 12996
DOI: 10.1039/C9CC06485K

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