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Issue 76, 2019
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Water-mediated C–H activation of arenes with secure carbene precursors: the reaction and its application

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Abstract

A water-mediated C–H activation using sulfoxonium ylides is reported, providing a general, green and step-economic approach to construct a C–C bond and varieties of useful N-heterocycle scaffolds. Notably, the “water-mediated” activation, in contrast to that in organic solvents, shows great potential in pharmaceutical, biochemistry and chemical industries.

Graphical abstract: Water-mediated C–H activation of arenes with secure carbene precursors: the reaction and its application

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Publication details

The article was received on 26 Jul 2019, accepted on 27 Aug 2019 and first published on 27 Aug 2019


Article type: Communication
DOI: 10.1039/C9CC05804D
Chem. Commun., 2019,55, 11418-11421

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    Water-mediated C–H activation of arenes with secure carbene precursors: the reaction and its application

    R. Nie, R. Lai, S. Lv, Y. Xu, L. Guo, Q. Wang and Y. Wu, Chem. Commun., 2019, 55, 11418
    DOI: 10.1039/C9CC05804D

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